Glybenclamide Cas nimewo: 10238-21-8 Fòmil molekilè: C23H28ClN3O5S
5-CHLORO-N-[2-[4-[[[(CYCLOHEXYLAMINO)KARBONYL]AMINO]-SULFONYL]FENYL]ETHYL]-2-METOXYBENZAMIDE
5-CHLORO-N-[2-[4-[[[(CYCLOHEXYLAMINO)KARBONYL]AMINO]SULFONYL]FENYL]ETHYL]-2-METOXYBENZAMIDE
5-CHLORO-N-[4-(CYCLOHEXYLUREIDOSULFONYL)FENETHYL]-2-METOXYBENZAMIDE
GIBENCLAMIDE
GLIBENCLAMIDE
GLYBENCLAMIDE
GLYBENZCYCLAMIDE
GLYBURIDE
LABOTEST-BB LT00244861
MICRONAZ
NP-[2-(5-CHLORO-2-METOXYBENZAMIDO)ETHYL]BENZENESULFONYL-N'-CYCLOHEXYLUREA
1-((p-(2-(Chloro-o-anisamido)etil)fenil)sulfonil)-3-cyclohexyl ure
1-((p-(2-(chloro-o-anisamido)etil)fenil)sulfonyl)-3-cyclohexyl-ure
1-((p-(2-(chloro-o-anisamido)etil)fenil)sulfonil)-3-cyclohexylurea
1-(p-(2-(5-Chloro-2-methoxybenzamido)etil)benzènsulfonil)-3-cyclohexylurea
1-[[p-[2-(5-Chloro-o-anisamido)etil]fenil]sulfonyl]-3-cyclohexylurea
1-[[p-[2-(chloro-o-anisamido)etil]fenil]sulfonyl]-3-cyclohexyl-Ure
5-chloro-n-(2-(4-((((cyclohexylamino)carbonyl)amino)sulfonyl)phenyl)etil)-2
Abbenclamide
adiab
Pwen k ap fonn | 173-175 °C |
Dansite | 1.1805 (estimasyon ki graj) |
tanperati depo | Atmosfè inaktif, Tanperati chanm 2-8 ° C |
solubilite | etanòl: soluble 2mg/mL |
aktivite optik | N/A |
Aparans | White Crystalline Powder |
Pite | ≥98% |
Glyburide (10238-21-8) se yon dezyèm jenerasyon ajan ipoglisemi oral.Aji atravè kanal K+ ki depann de ATP (Kir6, KATP) block.1?Anpeche kouran Kir6 nan pankreyas la, sa ki lakòz yon ogmantasyon nan entraselilè Ca2+ ak sekresyon ensilin.Glyburide tou inibit recombinant CFTR Cl-chanèl ak yon IC50 nan 20 μM.2? Selil pèmeyab.
Yon sulfonilurea dezyèm jenerasyon ak aktivite ipoglisemi
Mande doktè konsèy an premye