Florfenicol Cas nimewo: 73231-34-2 Fòmil molekilè: C12H14Cl2FNO4S

Deskripsyon kout:

Nimewo Cas: 73231-34-2

Non chimik: Florfenicol

Fòmil molekilè: C12H14Cl2FNO4S

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Pwodwi detay

Tags pwodwi

Sinonim

2,2-dikloro-n-[(1r,2s)-3-fluoro-1-hydroxy-1-(4-methylsulfonylphenyl)propan-2-yl]acetamid
AQUAFEN FLORFENICOL NUFLOR
[r-(r*, r*)]-n-[1-(fluoromethyl)-2-hydroxy-2-(4-(methylsulforyl)phenyl)-ethyl]-2,2-dikloroacetamide
[R-(R*,S*)]-2,2-DICHLORO-N-[1-(FLUOROMETHIL)-2-IDROKSY-2-[4-(METHYLSULFONYL)PHENYL]ETHYL]ACETAMIDE
SCH-25298
(r-(r*,s*))-methyleste
2,2-dikloro-n-(1-(fluorometil)-2-hydroxy-2-(4-(methylsulfonyl)phenyl)etil
4-(2-((dichloroacetyl)amino)-3-fluoro-1-hydroxypropyl)-benzènsulfonicaci
Florfeniol
FLUPROFÈN
Fluorothiamphenicol
Sch-25298, Aquafen
Acetamid, 2,2-dikloro-N-(1S,2R)-1-(fluorometil)-2-hydroxy-2-4-(methylsulfonyl)phenylethyl-
2,2-Dichloro-N-[(1S,2R)-1-(fluorometil)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl]acetamide
Aquaflor
Aquafen, Nuflor, SCH-25298, [R-(R*,S*)]-2,2-Dichloro-N-[1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl ]acetamid
2,2-Dichloro-N-(1-(fluoromethyl)-2-hydroxy-2-(4-(methylsulfonyl)phenyl)ethyl)acetamid
2,2-Dichloro-N-[(1R,2S)-3-fluoro-1-hydroxy-1-(4-methylsulfonylphenyl)propan-2-yl]acetamid

Pwodwi spesifikasyon

Pwen k ap fonn	153 °
Dansite	1.451±0.06 g/cm3 (Prevwa) 1.1782 (estimasyon ki graj)
tanperati depo	2-8 °C
solubilite	Soluble nan etanòl a 25mM ak nan DMSO a 100mM
aktivite optik	N/A
Aparans	Blan ak Off-blan
Pite	≥98%

Deskripsyon

Florfenicol se yon antibyotik fliyò gwo spectre ak yon dérivés thiamphenicol (Atik No. 21357).Li aktif kont izole klinik moun nan bakteri enterik, ki gen ladan E. coli, Klebsiella, Enterobacter, Citrobacter, P. mirabilis, ak Salmonèl (MIC).₅₀s = 6.3-12.5 μg/ml).Florfenicol aktif tou kont izole klinik divès kalite patojèn nan aparèy respiratwa bovine ak porsin, ki gen ladan P. multocida, A. pleuropneumoniae, ak B. bronchiseptica (MIC).₅₀s = 0.25-4 μg/ml).Li inibit aktivite peptidyl transferaz nan ribosome 70S izole nan E. coli lè yo itilize nan yon konsantrasyon 1 mM.Yo te itilize fòmilasyon ki gen florfenicol nan tretman maladi respiratwa enfektye nan bèt.

itilizasyon ak dòz

Li se yon kalite dwòg anti-bakteri.Li se itilize kòm veterinè dwòg antimikwòb pou trete maladi bakteri nan kochon, poul ak pwason.Li gen bon efikasite nan trete maladi enfeksyon nan kochon, poul ak pwason pwovoke pa bakteri sansib, espesyalman pou trete enfeksyon respiratwa ak enfeksyon entesten.